Injectable Corticosteroids
Injectable Corticosteroids
By Elizabeth Scherer
Discovery Communications, LLC.
Corticosteroids are medications used to reduce swelling and pain. Doctors sometimes inject them directly into the affected joint to treat pain from osteoarthritis. Although pill forms are available, their long-term side effects decrease their usefulness.
Corticosteroid injections are usually limited to 3 or 4 in the same joint per year. Repeated doses can permanently damage cartilage. Doctors typically only use corticosteroid injections for people who do not respond to or cannot tolerate other therapies.
How Injectable Corticosteroids Work
Corticosteroids affect your immune system. Normally, an injury causes inflammation. Blood vessels swell and irritants are released. Infection-fighting white blood cells then enter the injured area, adding to the irritation and swelling. Corticosteroids change the activity of the white blood cells so they are less able to move towards inflamed areas.
Possible Side Effects of Injectable Corticosteroids
Injectable corticosteroids can cause a wide range of side effects due to their effect on the immune system. Long-term use of corticosteroids can lead to brittle and fractured bones. Frequent injections can destroy joint cartilage. You should avoid exercise after an injection, because it can make side effects worse.
Bothersome Side Effects
Let your doctor know if you have any of these side effects. These are most often seen with long-term usage.
acne
a red, round face, called Cushing's syndrome
bloating
increased blood glucose levels in people with diabetes
increased risk of infection
high blood pressure
increased eye pressure, called glaucoma
mood changes
muscle weakness
slow healing of wounds
weight gain
Possible Drug Interactions With Injectable Corticosteroids
To help you avoid unnecessary side effects, don't take these with any other medications until you talk with your doctor. Tell your doctor about all other drugs you are taking - it's even a good idea to let your doctor see your other prescription containers. Not all drugs in the categories listed below will react with injectable corticosteroids - your doctor is the best judge. Always check with your doctor to be sure.
Drugs to Avoid With Injectable Corticosteroids
antibiotics
blood thinners
decongestants that contain the active ingredient ephedrine
heart medications
hormones, such as oral contraceptives
immunosuppressants, such as cyclosporine
NSAIDs
seizure medications
tuberculosis medications
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